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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/11034

Title: Preliminary toxicity study on the individual and combined effects of Citrullus colocynthis and Nerium oleander in rats.
Authors: Al-Yahya, M.A.
Keywords: Citrullus colocynthis
Nerium oleander
Toxicity
Issue Date: 2000
Publisher: Fitoterapia
Citation: 71: 385-391
Abstract: The toxicity of diet containing 10% of Citrullus colocynthis fruits or 10% of Nerium oleander leaves or their 1:1 mixture (5%+5%) for rats treated for 6 weeks was determined. Dullness, ruffled hair, decreased body weight gains and feed efficiency, and enterohepatonephropathy characterised treatment with C. colocynthis and N. oleander given alone. Diarrhoea was a prominent sign of C. colocynthis poisoning. Organ lesions were accompanied by leucopenia, anaemia and alterations in serum AST, ALT and ALP activities and concentrations of total protein, albumin, urea, bilirubin and other serum constituents. Feeding the mixture of C. colocynthis and N. oleander caused more marked effects and death of rats.
URI: http://hdl.handle.net/123456789/11034
Appears in Collections:College of Science

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