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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/11175

Title: Effect of Walterinnesia aegyptia, Cerastes cerastes and Bitis arietans venoms on liver functions of male rats. Pakistan
Authors: Alhazza, I. M.
Issue Date: 2001
Publisher: J. Zool., Pakistan,
Citation: 33(2):157-165.
Abstract: The effect of Walterinnesia aegyptia, Cerastes cerastes and Bitis arietans venoms (½, 1/5 and 1/10 of LD50) on liver function were studied at different time intervals. The blood glucose level elevated significantly inthe rats treated with ½ LD50 of venom of B. arietans, while it lowered significantly in the rats injected with 1/5 and ½ LD50 of W. aegyptia and C. cerastes venoms. Both blood cholesterol and triglycerides concentration decreased in the rats treated with any of the three venoms at doses level of 1/5 and ½ LD50. Blood alkaline phosphatase activity of the rats treated with 1/5 and ½ LD50 of W. aegyptia and Cerastes cerastes venoms elevated significantly. B. arietans venom had no significant influence on alkaline phosphatase or aspartate amino transferase activities. Both of AST and alanine amino transferase activities elevated significantly in the rats injected with ½ LD50 of the W. aegyptia and C. cerastes venoms. No histological changes were observed in the liver of rats given 1/10 LD50 of the three venoms. Haemorrhage was noticed in all sections of rats injected with ½ and 1/5 LD50 of the tested venoms. Some histological changes were recorded in case of ½ and 1/5 LD50 of the venoms.
URI: http://hdl.handle.net/123456789/11175
Appears in Collections:College of Science

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