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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/17149

Title: SYNTHESIS, CONFORMATIONAL ANALYSIS AND ANTITUMOR TESTING OF 5-(Z)-ARYLIDENE-4-IMIDAZOLIDINONE DERIVATIVES
Authors: A I Khodair
H I El-subbagh
A M Al-obaid
Issue Date: 1998
Publisher: GPSS
Abstract: A series of 5-(Z)-arylidene-2-amino-4-imidazolidinones 16–34, 5-(Z)-arylidene-2-(2-carboxyphenylamino)-4-imidazolidinones 35–41, 5-(Z)-arylidene-3-aminomethyl-2-thioxo-4-imidazolidinones 42–55 and 5-(Z)-arylidene-3-aminomethyl-2-methylmercapto-4-imidazolidinones 56–67 have been synthesized via two different routes. Conformational analysis and antitumor activities have been studied. The antitumor activity of these compounds showed broad spectrum of activity against a wide range of different human cell lines of nine tumor subpanels causing both cytostatic and cytotoxic potency. DOI: 10.1080/10426509808035741
URI: http://hdl.handle.net/123456789/17149
Appears in Collections:College of Pharmacy

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