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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/17171

Title: Differential pulse polarographic assay of tolmetin sodium capsules.
Authors: H A al-Khamees
A M al-Obaid
K A al-Rashood
, M E Mohamed
Issue Date: 1999
Publisher: J Pharm Biomed Anal
Abstract: Differential pulse polarography (DPP) is proposed as a direct method for the quantitation of tolmetin sodium in a capsule formulation (Tolectin--200 mg as the sodium dihydrate salt). Classical direct-current (DC) polarography has been employed to investigate the nature of the reduction occurring at the surface of the dropping mercury electrode (DME) using acetate buffer of pH 5.0 as the supporting electrolyte. The mean value of the results obtained by DPP expressed as a percentage of the stated amount, and the standard deviation, were found to be 99.87 +/- 0.43. The standard addition procedure used to assess the accuracy of the proposed method gave a mean percentage recovery of the total drug of 100.15 +/- 0.75%.
URI: http://hdl.handle.net/123456789/17171
Appears in Collections:College of Pharmacy

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