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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/17531

Title: Studies on the antiinflammatory, antipyretic and analgesic activities of santonin
Authors: : al-Harbi MM
Qureshi S
Ahmed MM
Raza M
Issue Date: 1994
Abstract: Santonin, a sesquiterpene lactone, commonly found in the plants of the family Compositae was found to show significant antiinflammatory activity on acute inflammatory processes. The activity profile of santonin closely resembled that of a standard non-steroidal antiinflammatory drug, diclofenac sodium. It also showed a significant inhibitory effect on granuloma formation; however, this effect of santonin was less pronounced as compared to diclofenac sodium. Santonin caused a significant antipyretic effect in mice, which was found to be independent of the route of administration of the drug. It also increased the hot plate reaction time of treated mice, similar to morphine.
URI: http://hdl.handle.net/123456789/17531
Appears in Collections:College of Pharmacy

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