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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/18438

Title: Flow-injection chemiluminometric analysis of somebenzamides by their sensitizing effect on the cerium-sulphitereaction
Authors: A. Aly, Fatma.
A. Alarfaj, Nawal.
A. Alwarthan, Abdulrahman.
Keywords: Benzamides; Chemiluminescence; Cerium(IV)-sulphite reaction; Pharmaceuticals; Biological fluids
Issue Date: 2001
Publisher: © 2001 Elsevier Science B.V.
Citation: Talanta 54 (2001) 715–725
Abstract: A simple, highly sensitive chemiluminescent method using flow injection is described for the determination of threesubstituted benzamides, namely: sulpiride, sultopride and tiapride. The method is based on the sensitizing effect ofthese drugs on the chemiluminometric oxidation of sulphite by cerium(IV). The different experimental parametersaffecting the chemiluminescence intensity were carefully studied and incorporated into the procedure. The methodpermits the determination of 0.05–2.5 µg ml−1sulpiride, 0.01–2.5µg ml−1sultopride hydrochloride and 0.01–1.5µg ml−1tiapride hydrochloride with minimum detectability of 0.01µg ml−1. The method was applied to thedetermination of these benzamides in pharmaceutical preparations and biological fluids.
URI: http://hdl.handle.net/123456789/18438
ISSN: 0039-9140
Appears in Collections:College of Science

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