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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/18534

Title: Antimicrobial Activity and Phytochemical Analysis of Polygonum Aviculare L.
Authors: M.H. Salama, Hediat.
Marraiki, Najat.
Keywords: Polygonum aviculare, antimicrobial activity, phytochemical analysis, minimum inhibitory concentration, minimum bactericidal concentration
Issue Date: 2009
Publisher: Australian Journal of Basic and Applied Sciences, 3(3): 2008-2015, 2009
Citation: Australian Journal of Basic and Applied Sciences, 3(3): 2008-2015, 2009
Abstract: Polygonum aviculare (Polygonaceae) is an herb commonly distributed in Mediterranean coastal regions in Egypt and used in folkloric medicine. Organic and aqueous solvent extracts and fractions of Polygonum aviculare were investigated for antimicrobial activities on several microorganisms including bacteria and fungi. The phytochemical constituents of the air dried powered plant parts were extracted using aqueous and organic solvents (acetone, ethanol, chloroform and water). The antimicrobial activity of the concentrated extracts was evaluated by determination of the diameter of inhibition zone against both Gram-negative and Gram-positive bacteria and fungi using paper disc diffusion method. Results of the phytochemical studies revealed the presence of tannins, saponins, flavonoids, alkaloids and sesquiterpenes and the extracts were active against both Gram - negative and Gram - positive bacteria. Chloroform extract gave very good and excellent antimicrobial activity against all tested bacteria and good activity against all tested fungi except Candida albicans. Structural spectroscopic analysis that was carried out on the active substances in the chloroform led to the identification of panicudine (6- hydroxy-11- deoxy- 13 dehydrohetisane). Evaluation of the antimicrobial activity of panicudine indicated significant activity against all Gram-negative and Grampositive organisms tested. Panicudine displayed considerable activity against the tested fungi with the exception of Candida albicans. The antimicrobial activity of the extracts were unaffected after exposure to different heat treatments, but was reduced at alkaline pH. Studies on the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of panicudine on the test organisms showed that the lowest MIC and the MBC were demonstrated against Salmonella paratyphi, Bacillus subtilis and Salmonella typhi and the highest MIC and MBC was exhibited againstStaphylococcus aureus
URI: http://hdl.handle.net/123456789/18534
ISSN: ISSN 1991-8178
Appears in Collections:College of Science

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