King Saud University Repository >
King Saud University >
Science Colleges >
College of Science >
College of Science >

Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/18716

Title: Fluorimetric determination of isoxsuprine hydrochloride inpharmaceuticals and biological fluids
Authors: A. Alarfaj, Nawal.
Keywords: Cerium; Isoxsuprine hydrochloride; Pharmaceuticals; Biological samples; Spectrofluorimetry
Issue Date: 2002
Publisher: © 2002 Elsevier Science B.V.
Citation: Journal of Pharmaceutical and Biomedical Analysis
Abstract: Two simple and highly sensitive fluorimetric methods have been developed for the determination of isoxsuprinehydrochloride in bulk, in dosage forms and in biological fluids. The first method involves the direct measurement ofthe native fluorescence of the drug in the concentration range 0.4–4.0µg ml−1, the second method is based on theoxidation of isoxsuprineHCl with cerium(IV) followed by fluorimetric measurement in the concentration range0.02–0.2µg ml−1. The average % found were 99.9± 0.78 and 100.0± 0.62 for the two methods, respectively. Theminimum detectability (3 SB) were 0.11 and 0.007 µg ml−1 for the two methods, respectively. The methods resultsshowed insignificant difference with those of the official method.
URI: http://hdl.handle.net/123456789/18716
ISSN: 0731-7085
Appears in Collections:College of Science

Files in This Item:

File Description SizeFormat
نموذج 216.81 kBUnknownView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


DSpace Software Copyright © 2002-2009 MIT and Hewlett-Packard - Feedback