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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/3031

Title: Hepatoprotective properties of Commiphora Opobalsamum ("balessan"), a traditional medicinal plant of Saudi Arabia
Authors: Al-Howiriny, T.A.
Al-Sohaibani, M.O.
Al-Said, M.S.
El-Tahir, K.H.
Rafatullah, S.
Keywords: Properties
Hepatoprotective
Opobalsamum
Commiphora
Balessan
Traditional
Medicinal Plant
Saudi Arabia
Issue Date: 2004
Publisher: Bioscience Ediprint
Citation: Drugs Under Experimental and Clinical Research: 30 (5/6); 213-220
Abstract: The hepatoprotective activity of an ethanolic extract of Commiphora opobalsamum ("Balessan") was investigated in rats by inducing hepatotoxicity with carbon tetrachloride:liquid paraffin (1:1). This extract has been shown to possess significant protective effect by lowering serum transaminase levels (serum glutamate oxaloacetate transaminase and serum glutamate pyruvate transaminase), alkaline phosphatase and bilirubin. Pretreatment with an extract of Balessan prevented the prolongation of the barbiturate sleeping time associated with carbon tetrachloride-induced liver damage in mice. On the other hand, CO1/induced low-level nonprotein sulfhydryl concentration in the liver was replenished by the Balessan extract. These data suggest that the plant C. opobalsamum may act as an antioxidant agent and may have a hepatoprotective effect.
Description: Corresponding Author: Mr. S. Rafatullah, Medicinal, Aromatic and Poisonous Plants Research Center (MAPPRC), College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia. Email: srafat@ksu.edu.sa
URI: http://hdl.handle.net/123456789/3031
ISSN: 0378-6501
Appears in Collections:College of Pharmacy

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