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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/3734

Title: Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats
Authors: Mahgoub, Afaf
El-Medany, Azza
Mustafa, Ali
Arafah, Maha
Moursi, Mahmoud
Keywords: Ulcerative
Colitis
IBD
Inflammatory
Perpetuation
Etiology
Issue Date: 2005
Publisher: Elsevier
Citation: Toxicology and Applied Pharmacology: 205; 43-52
Abstract: Ulcerative colitis is a common inflammatory bowzl disease (IBD) of unknown etiology. Recent Studies have revealed the rule of some microorganisms in the initiation and perpetuation of IBD. The role of antibiotics in the possible modulation or colon inflammations still uncertain. In the study, we evaluated the effects of two macrolides namely azithromycin and erythromycin at different doses on the exteddnt and severity of ulcerative colitis caused by administration of 3% acetic acid in rats. The lesiors and the inflammatory response were assessed by histrology and measurement of mycloperoxides (MPO) activity
Description: Department of Pharmacology, College of Medicine, King Saud University, Riyadh
URI: http://hdl.handle.net/123456789/3734
ISSN: 0041-008X
Appears in Collections:College of Medicine

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