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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/4214

Title: Effect of alpinia galanga treatment on cytological and biochemical changes induced by cyclophosphamide in mice
Authors: Qureshi, S.
Shah, A.H.
Ahmed, M.M.
Rafatullah, S.
Bibi, F.
Al-bekairi, A.M.
Keywords: Effect
Alpinia
Cytological
Biochemical
Induced
Cyclophosphamide
Mice
Treatment
Galanga
CP-treatment
Issue Date: 1994
Publisher: Swets & Zeitlinger
Citation: Int. J. Pharmacog: 32 (2); 171-177
Abstract: An ethanol extract of Alpinia galanga was administered to mice. This treatment did not affect the number of micronucleated polychromatic erythrocytes (PCE) in bone marrow cells, alter the protein and nucleic acid contents in liver and testes, or cause mitodepression of bone marrow. Cyclophosphamide (CP) induced micronucleated PCE, and A. galanga treatment significantly reduced this effect without altering cytotoxicity. The minimum effective dose of A. galanga extract required to produce this effect was 125 mg/kg body weight. Biochemical changes caused by CP-treatment in the liver of treated animals were also significantly inhibited by A. galanga treatment.
URI: http://hdl.handle.net/123456789/4214
ISSN: 0925-1618
Appears in Collections:College of Pharmacy

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