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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/4257

Title: Cytotoxic lupane-, secolupane-, and oleanane-type triterpenes from Viburnum awabuki
Authors: El-Gamal, Ali A.
Keywords: Viburnum Awabuki
Triterpenes
Lupane
Oleanane
Cytotoxicity
Issue Date: 16-Feb-2008
Publisher: Taylor & Francis
Citation: Natural Product Research: 22(3); 191–197
Abstract: Bioassay-guided fractionation of the methanolic extract of Viburnum awabuki afforded two new lupane triterpene derivatives; 6 -hydroxyl-3,20-dioxo-30 norlupane-28-oic acid (1) and 3,4-secolup-4,20-dihydroxy-3,28-dioic acid-3-oic acid methyl ester (2), along with seven known lupane and oleanane-type triterpenes (3–9). The structure of the isolated compounds was assigned using different spectroscopic techniques including 1D and 2D NMR. The 13CNMR data of compounds 5 and 9 is reported for the first time. Triterpenes 1, 2, and 7–9 showed in vitro cytotoxic activity against several tumor cell lines.
Description: Email: aelgamal00@yahoo.com Present address: Faculty of Pharmacy, Department of Pharmacognosy, King Saud University, P.O. box 22452, Riyadh -11495, Saudi Arabia.
URI: http://dx.doi.org/10.1080/14786410701761019
http://hdl.handle.net/123456789/4257
ISSN: 1478-6419
Appears in Collections:College of Pharmacy

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