|
DSpace at King Saud University >
King Saud University >
COLLEGES >
Health Colleges >
College of Pharmacy >
College of Pharmacy >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/5665
|
| Title: | Gastroprotective activity of ginger Zingiber officinale Rose, in Albino rats |
| Authors: | Al-Yahya, M.A.
Ageel, A.M.
Rafatullah, S.
Mossa, J.S.
Parmar, N.S.
Tariq, M. |
| Keywords: | Activity
Gastroprotective
Ginger Zingiber
Officinale Rose
Albino
Rats |
| Issue Date: | 1989 |
| Publisher: | Institute for Advanced Research in Asian Science and Medicine |
| Citation: | American Journal of Chinese Medicine: 17 (1-2); 51-56 |
| Abstract: | The cytoprotective and gastric anti-ulcer studies of ginger have been carried out in albino rats.
Cytodestruction was produced by 8 0% ethanol, 0 . 6M H C 1 , 0 . 2M NaOH and 2 5% NaCl. Whereas gastric ulcers
were produced by ulcerogenic agents including indomethacin, aspirin and reserpine, beside hypothermic restraint
stress and by pylorus ligated Shay rat technique. The results of this study demonstrate that the extract in the dose
of 5 0 0 mg/kg orally exert highly significant cytoprotection against 8 0% ethanol, 0 . 6M HC1, 0 . 2M NaOH and
25% NaCl induced gastric lesions. The extract also prevented the occurrence of gastric ulcers induced by nonsteroidal
anti-inflammatory drugs (NSAIDs) and hypothermic restraint stress. These observations suggest
cytoprotective and anti-ulcerogenic effect of the ginger. |
| Description: | Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy,
King Saud University, Riyadh-11451, Saudi Arabia
Tel.: (+9661)4677262; Fax: +96614677245
Email: alyahya@ksu.edu.sa |
| URI: | http://hdl.handle.net/123456789/5665 |
| Appears in Collections: | College of Pharmacy
|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
|
