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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/5704

Title: Studies on rut a chalepensis:an ancient medicinal herb still used in traditional medicine
Authors: Al-Said, Mansour S.
Ageel, A.M.
Tariq, M.
Al-Yahya, M.A.
Rafatullah, S,
Ginnawi, O.T.
Keywords: Studies on Rut
Ancient Medicinal
Herb Still
Traditional Medicine
Issue Date: 1990
Publisher: Elesiever Scientific Publishers
Citation: Journal of Ethnopharmaeology: 28; 305-312
Abstract: An ethanolic extract of the aerial parts of Ruta chalepensis was studied for its anti-inflammatory, antipyretic, analgesic and CNS depressant activities. The extract produced a significant inhibition of carrageenaninduced paw oedema and cotton pellet granuloma in rats. The studies on spontaneous motor activity in mice and conditioned avoidance responding (CAR) in rats showed a dose-dependent depression of the central nervous system in treated animals. Reduction of yeast-induced hyperthermia in mice confirmed its reputed antipyretic activity. The extract did not produce any significant changes in prothrombin time and fibrinogen level. It also failed to produce any analgesic activity in the hot plate reaction-time test in mice. Phytochemical screening of the aerial parts of the plant showed the presence of alkaloids, flavonoids, coumarins, tannins, volatile oil, sterols and/or triterpenes.
Description: Departments of Pharmacognosy and Pharmacology and Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, King Saud University, Riyadh-1H51 (Saudi Arabia)
URI: http://hdl.handle.net/123456789/5704
ISSN: 0378-8731
Appears in Collections:College of Pharmacy

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