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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/6280

Title: A Study of the effects of different disinfectants used in riyadh hospitals and their efficacy against methicillin resistant staphylococcus aureus (MRSA)
Authors: Baddour, Manal M
Keywords: Effects of different disinfectants
Riyadh hospitals
Methicillin resistant Staphylococcus aureus (MRSA)
Bactericidal activity
MRSA ATCC 33591
Issue Date: Apr-2008
Citation: Saudi Pharmaceutical Journal:16(2);165-170
Abstract: Methicillin resistant Staphylococcus aureus (MRSA) and the means of controlling it, continue to be of major interest to the healthcare community. The bactericidal activity of some disinfectants which are in common use in seven major tertiary care hospitals in Riyadh was tested against two control strains of S. aureus, namely MRSA ATCC 33591 and Methicillin sensitive Staphylococcus aureus (MSSA) ATCC 29213. The disinfectants tested in this study were a group used for hand antisepsis (Purell, EZclean, Cida stat and Manorapid Synergy) and another group used for environmental disinfection (Combi spray, Tristel fusion, Alphadine, Isopropanol, Presept and Diesin). Presept, diesin and tristel fusion had a remarkable effect on the tested strains, both methicillin sensitive and methicillin resistant. There was hardly any noticeable difference between the effects on either (P> 0.05). On the other hand, Purell and EZclean and Manorapid Synergy hand rubs had a relatively weak action after 15 and 30 minutes while their effect was better after 1 and 2 hours. There were no observable differences between their effects on MRSA or MSSA, P>0.05. Cida stat had a remarkably pronounced effect against both MRSA and MSSA. Contrary to some previous reports, this study has also proven that chlorhexidine and quaternary ammonium compounds show comparable efficacy against both MRSA and MSSA.
URI: http://hdl.handle.net/123456789/6280
Appears in Collections:Saudi Pharmaceutical Society

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