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Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/6493
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| Title: | Sythesis of some new 4-(3H)-quinazoline analogs as potential antioxidant agents |
| Authors: | Al-Omar, M.A.
El-Azab, Adel S.
El-Obeid, H.A
Hamide, Abdel, S.G. |
| Keywords: | Potential antioxidant
Chemistry
Exprimental Chemistry |
| Issue Date: | 2006 |
| Publisher: | King Saud University |
| Citation: | Journal of Saudi Chemical Society:10; 113 |
| Abstract: | A new series of 6-iodo-2-propyl-4(3H)-quinazolinone and its fused heterocyclic
were prepared and screened for their antioxidant activity. It was found that compounds 4, 5,
7, 9, 10, 20 and 24 inhibit aldehyde oxidase exclusively by more than 98%. This type of
inhibition was found to be competitive with Ki value ranging from 50-400 mM with respect
to aldehyde oxidase. |
| Description: | Department of Pharmaceutical Chemistry, College of Pharmacy,
King Saud University, P.O. Box 2457, Riyadh-11451
Saudi Arabia |
| URI: | http://hdl.handle.net/123456789/6493 |
| Appears in Collections: | College of Pharmacy
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