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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/6493

Title: Sythesis of some new 4-(3H)-quinazoline analogs as potential antioxidant agents
Authors: Al-Omar, M.A.
El-Azab, Adel S.
El-Obeid, H.A
Hamide, Abdel, S.G.
Keywords: Potential antioxidant
Exprimental Chemistry
Issue Date: 2006
Publisher: King Saud University
Citation: Journal of Saudi Chemical Society:10; 113
Abstract: A new series of 6-iodo-2-propyl-4(3H)-quinazolinone and its fused heterocyclic were prepared and screened for their antioxidant activity. It was found that compounds 4, 5, 7, 9, 10, 20 and 24 inhibit aldehyde oxidase exclusively by more than 98%. This type of inhibition was found to be competitive with Ki value ranging from 50-400 mM with respect to aldehyde oxidase.
Description: Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh-11451 Saudi Arabia
URI: http://hdl.handle.net/123456789/6493
Appears in Collections:College of Pharmacy

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