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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/7457

Title: Treatment of chronic hepatitis C genotype IV with interferon-ribavirin combination in Saudi Arabia: a multicentre study
Authors: Al-Faleh, F.Z.
Aljumah, A.
Rezeig, M.
Al-Kanavvi, M.
Al-Otaibi, M.
Alahdal, M.
Al-Humayed, S.
Mayet, I.
Al-Juhani, M.
Al-Karawi, M.
George, K.
Sbeih, F.
Keywords: Hepatitis C,
Genotype 4
Interferon-x
Ribavirin
Saudi Arabia
Medical Sciences
Issue Date: 2000
Publisher: Journal of Viral Hepatitis
Citation: Journal of Viral Hepatitis: 7; 287-291
Abstract: Between 1996 and 1997. we conducted a multicentre study to assess the effect of combination therapy of interferon (IFN) + ribavirin on chronic hepatitis C genotype 4. Ninety-seven patients were enrolled. Sixty-eight patients (47 male and 21 female) were uon-responders to previous therapy with [FN (Group I). Twenty-nine patients 119 male and 10 female) were new (Group 11). Following treatment with IF.V 23% in Group I and 9% in Group II had a sustained biochemical response. Only 12% In Group I and 5% in Group II achieved a sustained virologiea! response. Virus load was found to be the major factor determining response, followed by histology grading and staging, bike HCV genotype 1, HCV genotype 4 seems to have a poor response to therapy.
URI: http://hdl.handle.net/123456789/7457
Appears in Collections:College of Medicine

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