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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/7894

Title: Effect of Short-Term Use of Different Non-Steroidal Anti-Inflammatory Drugs on Renal Function During Fasting in Ramadan
Authors: Al-Arfaj, Hussein F.
Alballa, Suliman .R
Alhaider, Abdulqader A.
Huraib, Sameer O.
Al-Arfaj, Abdurahman
Bamgboye, Elijah
Keywords: NSAIDs
Renal function
Anti-inflammatory drugs
Issue Date: 1995
Publisher: Saudi Center for Organ Transplantation
Citation: Saudi Journal of Kidney Disease & Transplantation: 6 (1); 9-14
Abstract: This study was conducted to determine the combined effect of Ramadan fasting and short-term use of different non-steroidal anti-inflammatory drugs (NSAIDs) on renal function in healthy volunteers. The study subjects were assigned to six different groups, five of whom took different NSAIDs (namely nabumetoce, indotaethacin, diclofenac, sulindac, tenoxicam) and the sixth was a control group. Data were collected on serum sodium, chloride, potassium, urea; creatinine, bicarbonate and uric acid as well as urinary osmolarity, sodium, potassium, chloride and urea. These measurements were taken before fasting, 10 days into fasting while using NSAIDs, and five days after stopping the use of NSAIDs. The results showed slight changes in serum and urine measurements during fasting while using NSAIDs. These changes, although were significant in some cases, were within the normal range and were noted in all the study groups including the control group We conclude that short-term use of NSAIDs in healthy subjects during fasting is not associated with any major adverse effects on the renal function.
URI: http://hdl.handle.net/123456789/7894
Appears in Collections:King Khalid Hospital

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