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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/8732

Title: Synthesis and biological testing of new 1-adamantyl derivatives
Authors: Al Abdullah, Ebtehal Suliman
Keywords: Synthesis and Biological Testing
1-Adamantyl Derivatives
Antiviral
Anti-inflammatory
Antibacterial
Issue Date: 2007
Abstract: Several adamantane derivatives have long been known for their diverse biological properties, mainly as antiviral, antibacterial, antifungal and anti-inflammatory agents. Adamantyl derivatives were recently reported to possess 11b-HSD1 inhibitory activities. In addition, 1,2,4-triazole and 1,3,4-thiadiazole were reported to constitute the pharmacologically active moiety of several compounds. On these bases, new series of 1-adamantyl derivatives, in which the adamantyl moiety was attached to 1,2,4-triazole, 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole or 1,3,4- thiadiazole nucleus, have been synthesized as potential bioactive agents.
Description: Submitted in Partial Fulfillment of the Requirements for the Ph. D. Degree in Pharmaceutical Sciences "Pharmaceutical Chemistry" in the College of Pharmacy, King Saud University, 2007
URI: http://hdl.handle.net/123456789/8732
Appears in Collections:College of Pharmacy

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